Serum FSH, LH, and testosterone in /sup 60/Co. gamma. -irradiated male rats

Journal Article · Wed Nov 01 04:00:00 EST 1978 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3574783· OSTI ID:6528639

Cunningham, G R; Huckins, C

Adult male rats were exposed to 330 R of whole-body /sup 60/Co ..gamma.. irradiation. Groups of irradiated and nonirradiated control rats were killed at intervals up to 65 days after irradiation at the same time each day. Testes were examined histologically, and serum levels of FSH, LH, and testosterone were determined at each point, and intratesticular levels of testosterone in irradiated rats were not significantly different from those in controls at any interval. This would indicate that the selective absence of spermatogonia, spermatocytes, or spermatids at sequential intervals after irradiation did not directly or indirectly affect serum hormonal levels. Moreover, this dose of irradiation did not appear to alter the functional integrity of Sertoli and Leydig cells.

• Research Organization: Baylor College of Medicine, Houston, TX
• OSTI ID: 6528639
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 76:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560152* -- Radiation Effects on Animals-- Animals
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACUTE EXPOSURE
ACUTE IRRADIATION
ADULTS
AGE DEPENDENCE
ANDROGENS
ANDROSTANES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLOOD SERUM
BODY
COBALT 60
COBALT ISOTOPES
ELECTROMAGNETIC RADIATION
EXTERNAL IRRADIATION
FSH
GAMMA RADIATION
GONADOTROPINS
GONADS
HISTOLOGICAL TECHNIQUES
HORMONES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
KETONES
LABELLED COMPOUNDS
LH
MALE GENITALS
MALES
MAMMALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
QUANTITY RATIO
RADIATION EFFECTS
RADIATIONS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOISOTOPES
RADIOSENSITIVITY
RATS
RODENTS
STEROID HORMONES
STEROIDS
SUBLETHAL IRRADIATION
TESTES
TESTOSTERONE
TRACER TECHNIQUES
TRITIUM COMPOUNDS
VERTEBRATES
WHOLE-BODY IRRADIATION
YEARS LIVING RADIOISOTOPES