Body composition of adult cystic fibrosis patients and control subjects as determined by densitometry, bioelectrical impedance, total-body electrical conductivity, skinfold measurements, and deuterium oxide dilution

Journal Article · Wed Aug 01 04:00:00 EDT 1990 · American Journal of Clinical Nutrition; (USA)

OSTI ID:6525242

Newby, M J; Keim, N L; Brown, D L ^[1]

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1. Univ. of California, Davis (USA)

This study contrasts body compositions (by six methods) of eight cystic fibrosis (CF) subjects with those of eight control subjects matched for age, height, and sex. CF subjects weighed 84% as much as control subjects. Densitometry and two bioelectrical impedance-analysis methods suggested that reduced CF weights were due to less lean tissue (10.7, 9.5, and 10.4 kg). Total-body electrical conductivity (TOBEC) and skinfold-thickness measurements indicated that CF subjects were leaner than control subjects and had less fat (5.4 and 3.6 kg) and less lean (5.2 and 7 kg) tissue. D2O dilution showed a pattern similar to TOBEC (8.3 kg less lean, 2.7 kg less fat tissue). Densitometry estimates of fat (mass and percent) were not correlated (r less than 0.74, p greater than 0.05) with any other method for CF subjects but were correlated with all other methods for control subjects. CF subjects contained less fat and lean tissue than did control subjects. Densitometry by underwater weighing is unsuitable for assessing body composition of CF patients.

• OSTI ID: 6525242
• Journal Information: American Journal of Clinical Nutrition; (USA), Journal Name: American Journal of Clinical Nutrition; (USA) Vol. 52:2; ISSN 0002-9165; ISSN AJCNA
• Country of Publication: United States
• Language: English

Related Subjects

550901* -- Pathology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ADIPOSE TISSUE
ANIMAL TISSUES
BIOELECTRICITY
BODY
BODY COMPOSITION
CONNECTIVE TISSUE
DEUTERIUM
DISEASES
ELECTRICITY
HYDROGEN COMPOUNDS
HYDROGEN ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LIGHT NUCLEI
NUCLEI
ODD-ODD NUCLEI
OXYGEN COMPOUNDS
PATHOGENESIS
RESPIRATORY SYSTEM DISEASES
STABLE ISOTOPES
TISSUES
TRACER TECHNIQUES
WATER