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Sorption/desorption of ( sup 14 C)efrotomycin with soils

Journal Article · · Journal of Agricultural and Food Chemistry; (USA)
DOI:https://doi.org/10.1021/jf00093a062· OSTI ID:6521844
;  [1]
  1. Merck Sharp and Dohme Research labs., Rahway, NJ (USA)

The sorption and subsequent desorption of efrotomycin, which is being developed as a growth promoter in swine, was investigated in five soils of various physical and chemical properties. Sorption equilibration occurred within 7 h. Sorption distribution coefficients ranged from 8 to 290. The Freundlich constant, K, spanned a similar range as n values were near 1. The sorption distribution coefficients, K{sub d}, were not correlated with organic matter content; cation-exchange capacity; sand, silt, or clay content; or soil pH. Hysteresis was observed between the sorption and desorption isotherms for one of the soils. For four soils, only about 50% of the sorbed efrotomycin could be desorbed, even with organic solvents. Efrotomycin is classified as immobile in most soils by comparison of its K{sub oc} values (580-11,000) with those of other chemicals.

OSTI ID:
6521844
Journal Information:
Journal of Agricultural and Food Chemistry; (USA), Journal Name: Journal of Agricultural and Food Chemistry; (USA) Vol. 38:3; ISSN JAFCA; ISSN 0021-8561
Country of Publication:
United States
Language:
English