Evaluation of the potential carcinogenicity of 1,2-dibromo-3-chloropropane. Final report

Technical Report · Wed Jun 01 00:00:00 EDT 1988

OSTI ID:6521287

1,2-Dibromo-3-chloropropane is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is No Data. The potency factor (F) for 1,2-dibromo-3-chloropropane is estimated to be 1240 (mg/kg/day)(-1) placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, 1,2-dibromo-3-chloropropane is assigned a HIGH hazard ranking.

• Research Organization: Syracuse Research Corp., NY (United States)
• OSTI ID: 6521287
• Report Number(s): PB-93-185304/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
• Country of Publication: United States
• Language: English

Related Subjects

29 ENERGY PLANNING, POLICY, AND ECONOMY
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
CARCINOGENS
DATA PROCESSING
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
HYDROCARBONS
MATERIALS
NATIONAL ORGANIZATIONS
NEOPLASMS
ORGANIC COMPOUNDS
PHYSIOLOGY
PROCESSING
PROPANE
PUBLIC HEALTH
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT