Current treatment of Graves' disease
Journal Article
·
· Surg. Clin. North Am.; (United States)
OSTI ID:6518820
In this review we have described the rationale for the appropriate treatment of patients with Graves' disease. Because the etiology of this disorder remains obscure, its management remains controversial. Since antithyroid drugs and radioiodine became readily available in the early 1950s, they have been widely used for the treatment of thyrotoxicosis, and the number of cases treated surgically has markedly decreased. However, almost four decades of experience have disclosed an unexpectedly high incidence of delayed hypothyroidism after radioiodine treatment and a low remission rate after antithyroid therapy. As a result, surgery is again being advocated as the treatment of choice. The three modalities of treatment have different advantages and disadvantages, and selection of treatment is of importance. In principle, we believe that for most patients a subtotal thyroidectomy should be performed after the patient has been rendered euthyroid by antithyroid drugs. We attempt to leave a thyroid remnant of 6 to 8 gm.36 references.
- Research Organization:
- Kawasaki Medical School, Kurashiki, Japan
- OSTI ID:
- 6518820
- Journal Information:
- Surg. Clin. North Am.; (United States), Journal Name: Surg. Clin. North Am.; (United States) Vol. 2; ISSN SCNAA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Management of hyperthyroidism in children and adolescents
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Early results of $sup 125$I therapy of thyrotoxic Graves' disease
Journal Article
·
Wed May 01 00:00:00 EDT 1985
· J. Clin. Endocrinol. Metab.; (United States)
·
OSTI ID:5566050
Prospective study of the changes in thyrotropin binding inhibitory immunoglobulins in Graves' disease treated by subtotal thyroidectomy or radioactive iodine
Journal Article
·
Sun Jun 01 00:00:00 EDT 1980
· J. Clin. Endocrinol. Metab.; (United States)
·
OSTI ID:5220047
Early results of $sup 125$I therapy of thyrotoxic Graves' disease
Journal Article
·
Mon Apr 01 00:00:00 EDT 1974
· J. Nucl. Med., v. 15, no. 4, pp. 257-260
·
OSTI ID:4331393
Related Subjects
550600 -- Medicine
550604* -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
CHEMOTHERAPY
COMBINED THERAPY
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
ETIOLOGY
GLANDS
GOITER
HYPERTHYROIDISM
HYPOTHYROIDISM
IODINE ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
THERAPY
THYROID
THYROIDECTOMY
550604* -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
CHEMOTHERAPY
COMBINED THERAPY
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
ETIOLOGY
GLANDS
GOITER
HYPERTHYROIDISM
HYPOTHYROIDISM
IODINE ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
THERAPY
THYROID
THYROIDECTOMY