Thermoacoustic emission induced by deeply-penetrating radiation and its application to biomedical imaging
Thermoacoustic emissions induced by 2450 MHz microwave pulses in water, tissue-simulating phantoms and dog kidneys have been detected. The analytic signal magnitude has been employed in generating A-mode images with excellent depth resolution. Thermoacoustic emissions have also been detected from the dose-gradient at the beam edges of a 4 MeV x-ray beam in water. These results establish the feasibility of employing thermoacoustic signals in generating diagnostic images, and in locating x-ray beam edges during radiation therapy. A theoretical model for thermoacoustic imaging using a directional transducer has been developed, which may be used in the design of future thermoacoustic imaging system, and in facilitating comparisons with other types of imaging systems. A method of characterizing biological tissues has been proposed, which relates the power spectrum of the detected thermoacoustic signals to the autocorrelation function of the thermoacoustic source distribution in the tissues. The temperature dependence of acoustic signals induced by microwave pulses in water has been investigated. A microwave-induced thermoacoustic source capable of launching large aperture, unipolar ultrasonic plane wave pulses in water has been constructed.
- Research Organization:
- Arizona Univ., Tucson, AZ (USA)
- OSTI ID:
- 6518714
- Resource Relation:
- Other Information: Thesis (Ph. D.)
- Country of Publication:
- United States
- Language:
- English
Similar Records
TU-FG-BRB-09: Thermoacoustic Range Verification with Perfect Co-Registered Overlay of Bragg Peak onto Ultrasound Image
Thermoacoustic imaging over large field of view for three-dimensional breast tumor localization: A phantom study
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
IMAGE PROCESSING
DEPTH DOSE DISTRIBUTIONS
MICROWAVE RADIATION
BIOLOGICAL EFFECTS
ACOUSTICS
DOGS
ELECTRON BEAMS
KIDNEYS
PHANTOMS
TEMPERATURE DEPENDENCE
WATER
X RADIATION
ANIMALS
BEAMS
BODY
ELECTROMAGNETIC RADIATION
HYDROGEN COMPOUNDS
IONIZING RADIATIONS
LEPTON BEAMS
MAMMALS
MOCKUP
ORGANS
OXYGEN COMPOUNDS
PARTICLE BEAMS
PROCESSING
RADIATION DOSE DISTRIBUTIONS
RADIATIONS
SPATIAL DOSE DISTRIBUTIONS
STRUCTURAL MODELS
VERTEBRATES
560400* - Other Environmental Pollutant Effects
550602 - Medicine- External Radiation in Diagnostics- (1980-)