Duplex imaging and incidence of carotid radiation injury after high-dose radiotherapy for tumors of the head and neck

Journal Article · Sat Sep 01 04:00:00 EDT 1990 · Archives of Surgery (Chicago); (USA)

DOI:https://doi.org/10.1001/archsurg.1990.01410210107017· OSTI ID:6509113

Moritz, M W; Higgins, R F; Jacobs, J R ^[1]

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1. Wayne State Univ., Detroit, MI (USA)

Radiation-induced carotid artery disease following high-dose (greater than 50-Gy) radiotherapy for head and neck cancer may become more common as improved treatment results in longer survival. Duplex ultrasound scans were obtained in 91 consecutive patients to determine whether increased incidence and severity of extracranial carotid disease correlate with prior radiotherapy. Fifty-three patients who underwent radiotherapy an average of 28 months previously and 38 patients who received no radiotherapy were studied. Thirty percent of the irradiated group had lesions of the carotid arteries that were either moderate or severe vs only 6% of the control patients. Five patients were symptomatic; all had undergone radiotherapy. Long-term follow-up with sequential duplex ultrasound examinations is indicated in patients receiving high-dose radiotherapy for head and neck tumors, to detect radiation-induced carotid artery disease and prevent late sequelae.

• OSTI ID: 6509113
• Journal Information: Archives of Surgery (Chicago); (USA), Journal Name: Archives of Surgery (Chicago); (USA) Vol. 125:9; ISSN ARSUA; ISSN 0004-0010
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
DISEASES
DOSES
HEAD
MEDICINE
NECK
NEOPLASMS
NUCLEAR MEDICINE
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY
ULTRASONOGRAPHY
VASCULAR DISEASES