CT imaging of small animals using monochromatized synchrotron x rays

Conference · Wed Jan 01 04:00:00 EST 1992

OSTI ID:6501689

Dilmanian, F A; Rarback, H; Nachaliel, E; Rivers, M; Thomlinson, W C; Chapman, L D; Oversluizen, T; Slatkin, D N; Spanne, P; Spector, S ^[1]; Garrett, R F ^[2]; Luke, P N; Pehl, R; Thompson, A C ^[3]; Appel, R; Miller, M H ^[4]

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1. Brookhaven National Lab., Upton, NY (United States)
2. Australian Inst. of Nuclear Science and Engineering, Lucas Heights, NSW (Australia)
3. Lawrence Berkeley Lab., CA (United States)
4. A

Rats and chicken embryos were imaged in vivo with a prototype Multiple Energy Computed Tomography (MECT) system using monochromatized x rays from the X17 superconducting wiggler at the National Synchrotron Light Source. The CT configuration coated of a horizontal low-divergence, fan-shaped beam, 70 mm wide and 0.5 mm high, and a subject rotating about a vertical aids. A linear-array high-purity Ge detector with 140 elements, each 0.5 mm wide and 6 mm thick, was used with a data acquisition system that provides a linear response over almost six orders of magnitude of detector current. The dual photon absorptiometry (DPA) algorithm was applied to images of the rat head acquired at 20 and 45 keV to obtain two new images, one representing the low-Z, and the other the intermediate-Z clement group. The results indicate that the contrast resolution and the quantification accuracy of the images improve stepwise; first, with the monochromatic beam and, second, the DPA method. The system is a prototype for a brain scanner.

• Research Organization: Brookhaven National Lab., Upton, NY (United States)
• Sponsoring Organization: DOE; USDOE, Washington, DC (United States)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 6501689
• Report Number(s): BNL-48454; CONF-921005--30; ON: DE93009329
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCELERATORS
ANIMALS
BIRDS
CHICKENS
COMPUTERIZED TOMOGRAPHY
CYCLIC ACCELERATORS
DIAGNOSTIC TECHNIQUES
EMBRYOS
FOWL
IMAGE PROCESSING
MAMMALS
MONOCHROMATORS
NSLS
POSITIONING
PROCESSING
RADIATION SOURCES
RATS
RODENTS
SYNCHROTRON RADIATION SOURCES
SYNCHROTRONS
TOMOGRAPHY
VERTEBRATES