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Prevention of postvenographic thrombosis by heparin flush: fibrinogen uptake measurements

Journal Article · · AJR, Am. J. Roentgenol.; (United States)
The incidence of postphlebographic venous thrombosis was investigated by /sup 125/I-labeled fibrinogen uptake tests in 60 patients whose veins were flushed with saline solution containing 10,000 IU of heparin after leg phlebography. Ionic methylglucamine iodamide was used as the contrast medium. In six patients superficial thrombophlebitis extending from the contrast-medium injection site was observed after phlebography. The incidence of deep venous thrombosis was 3.3%, significantly less than that reported for studies using triiodinated ionic contrast media without flushing the veins with a heparin solution. It is comparable to the incidence of venous thrombosis reported after using nonionic contrast media. The authors conclude that flushing the veins with heparinized saline solution can improve the safety of phlebography considerably.
Research Organization:
Univ. of Vienna, Austria
OSTI ID:
6501146
Journal Information:
AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 143:3; ISSN AAJRD
Country of Publication:
United States
Language:
English