Assessment of renal function of workers simultaneously exposed to inorganic lead and cadmium

Journal Article · Fri May 01 04:00:00 EDT 1981 · J. Occup. Med.; (United States)

OSTI ID:6499928

Buchet, J P; Roels, H; Bernard, A Jr; Lauwerys, R

The renal function of a group of workers (n = 62) exposed simultaneously to lead and to cadmium was examined. The results were compared with those obtained in an earlier study of three groups of workers - one exposed to lead only, one exposed to cadmium only, and one not exposed to either of these metals (control group). No interaction between lead and cadmium is evidenced. The signs of renal dysfunction found in the group exposed simultaneously to lead and to cadmium can be ascribed to cadmium only. The results of this study have confirmed the authors' previous observations, that is, a moderate exposure to lead (plumbemia < 62 ..mu..g/100 ml and average duration of exposure = 13.2 years) does not seem to influence renal function; in adult male workers the critical levels of cadmium in blood and in urine are 1 ..mu..g/100 ml whole blood and 10 ..mu..g/g creatinine respectivly; the renal dysfunction induced by cadmium is both glomerular and tubular.

• Research Organization: Univ. of Louvain, Brussels, Belgium
• OSTI ID: 6499928
• Journal Information: J. Occup. Med.; (United States), Journal Name: J. Occup. Med.; (United States) Vol. 23:5; ISSN JOCMA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism &amp; Toxicology-- Man-- (-1987)
570000 -- Health &amp; Safety
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
BIOLOGICAL EFFECTS
BIOLOGICAL FUNCTIONS
BODY
CADMIUM
CHRONIC EXPOSURE
ELEMENTS
FUNCTIONS
INDUSTRIAL PLANTS
KIDNEYS
LEAD
METALS
ORGANS
PERSONNEL