Environmental Protection Agency's methodology for assessing risk of exposure to nasal carcinogens
Technical Report
·
OSTI ID:6496080
The U.S. Environmental Protection Agency has carried out risk assessments on a variety of chemicals that have been shown to induce nasal tumors in animals and/or humans. Human cancer-potency estimates, however, were not always based on the induction of nasal tumors. For those that were, studies employing the inhalation route of exposure were used, with one exception. Extrapolation from the inhalation to the oral route has not been attempted for nasal carcinogens. A variety of uncertainties in assessing potency of nasal carcinogens is being addressed.
- Research Organization:
- Environmental Protection Agency, Washington, DC (USA). Office of Health and Environmental Assessment
- OSTI ID:
- 6496080
- Report Number(s):
- PB-89-130496/XAB; EPA-600/D-88/242
- Country of Publication:
- United States
- Language:
- English
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54 ENVIRONMENTAL SCIENCES
AIR POLLUTION
CARCINOGENS
RESPIRATION
HAZARDOUS MATERIALS
RESPIRATORY SYSTEM
ENVIRONMENTAL EXPOSURE
INHALATION
LABORATORY ANIMALS
US EPA
INTAKE
MATERIALS
NATIONAL ORGANIZATIONS
POLLUTION
US ORGANIZATIONS
560300* - Chemicals Metabolism & Toxicology
500200 - Environment
Atmospheric- Chemicals Monitoring & Transport- (-1989)