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Comparative study of HPLC column packings for the separation of aromatic and polar compounds in fossil fuel liquids

Conference · · Am. Chem. Soc., Div. Fuel Chem., Prepr.; (United States)
OSTI ID:6494717

This paper reports a study on normal phase high performance liquid chromatography (HPLC) separations of aromatic and polar compounds using the following packing materials: Nucleosil NO/sub 2/; Nucleosil NH/sub 2/; Nucleosil CN; Nucleosil SA; Lichrosorb Si-5; Lichrosorb Al-5; and TSK 111. The retention data of model aromatic compounds on each stationary phase are summarized. The largest factor (K') was obtained by using Nucleosil NO/sub 2/ column, with the exception of activated alumina. The retention behavior of selected polar compounds is summarized. Good separation of polar compounds from aromatic hydrocarbons was obtained except for that on TSK 111. As TSK 111 has no polar group on it, interaction with polar group in sample molecule is weak. The rather strong retention of phenols and indoles will be due to their electrophilic nature. Polar compounds were preferentially retained on the stationary phases other than TSK 111. Gradient elution was carried out for rapid elution of strongly retained molecules. From the data obtained, it is considered that polar-polar interactions including hydrogen bonding or acid-base interaction are the predominant separation mechanism, although the effect of alkyl substitution, especially at sterically hindered positions to polar groups, is not negligible. HPLC separations on coal tar and heavy petroleum fractions are described and chromatograms are presented.

Research Organization:
Nippon Mining Co., Ltd., Tokyo, Japan
OSTI ID:
6494717
Report Number(s):
CONF-810308-(Vol.4)
Journal Information:
Am. Chem. Soc., Div. Fuel Chem., Prepr.; (United States), Journal Name: Am. Chem. Soc., Div. Fuel Chem., Prepr.; (United States) Vol. 26:2; ISSN ACFPA
Country of Publication:
United States
Language:
English