Design of a CZT based BreastSPECT system

Journal Article · Mon Jun 01 04:00:00 EDT 1998 · IEEE Transactions on Nuclear Science

DOI:https://doi.org/10.1109/23.681995· OSTI ID:649397

Singh, M; Mumcuoglu, E ^[1]

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1. Univ. of Southern California, Los Angeles, CA (United States)

A high-resolution SPECT instrument dedicated to breast imaging has been designed incorporating arrays of collimated Cadmium-Zinc-Telluride (CZT) detectors tiled on either a cylindrical surface or a hemispherical surface surrounding the breast. The performance characteristics of a three-segment rotating parallel-hole collimator as well as a stationary multiple pin-hole collimator were considered for the cylindrical system. A stationary multiple pin-hole collimated system was also considered for the hemispherical design. Monte Carlo studies suggest that at almost equal spatial resolution of 0.5 cm, the cylindrical design with parallel-hole collimator would have an approximately a factor of two higher geometrical efficiency than the hemispherical pin-hole collimated system including effects of attenuation in the breast. However, whereas the parallel-hole collimator must be rotated to acquire data from multiple angles of view, the pin-hole version has the advantage of recording data from 112 views in a stationary mode. Monte Carlo studies of filtered backprojections as well as a Bayesian reconstruction approach including attenuation and scatter within the breast, where the breast was modeled as a 15 cm hemisphere of uniform activity distribution containing three spherical lesions of diameters 1.0 cm, 0.7 cm and 0.5 cm respectively suggest that the 0.5 cm could be detected with either design in a one-hour SPECT study assuming a 10:1 tumor to background ratio. The authors conclude that a high resolution Breast SPECT instrument where the resolution is limited to about 0.5 cm is viable with CZT detectors.

• OSTI ID: 649397
• Report Number(s): CONF-971147--
• Journal Information: IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 3Pt2 Vol. 45; ISSN 0018-9499; ISSN IETNAE
• Country of Publication: United States
• Language: English

Related Subjects

44 INSTRUMENTATION
INCLUDING NUCLEAR AND PARTICLE DETECTORS
55 BIOLOGY AND MEDICINE
BASIC STUDIES
COLLIMATORS
DESIGN
IMAGE PROCESSING
MAMMARY GLANDS
NEOPLASMS
PERFORMANCE TESTING
SEMICONDUCTOR DETECTORS
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY