Meta-(I-131)iodobenzylguanidine uptake in a nonsecreting paraganglioma

Journal Article · Sat Sep 01 00:00:00 EDT 1984 · J. Nucl. Med.; (United States)

OSTI ID:6480716

Smit, A J; van Essen, L H; Hollema, H; Muskiet, F A.J.; Piers, D A

In a patient with a paraganglioma at the carotide bifurcation, intense uptake of meta-(I-131)iodobenzylguanidine (I-131 MIBG) in the tumor was found. There was no clinical or biochemical evidence for catecholamine secretion by the tumor, although analysis of the tissue revealed that catecholamine biosynthesis took place. The authors conclude that accumulation of I-131 MIBG may occur in a paraganglioma, but does not necessarily indicate endocrine activity of the tumor.

• Research Organization: Univ. Hospital, Groningen, Netherlands
• OSTI ID: 6480716
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:9; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINES
AROMATICS
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL ACCUMULATION
BIOSYNTHESIS
BLOOD VESSELS
BODY
BODY AREAS
CARBONIC ACID DERIVATIVES
CARDIOVASCULAR SYSTEM
CAROTID ARTERIES
CATECHOLAMINES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
GANGLIONS
GUANIDINES
HOURS LIVING RADIOISOTOPES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NECK
NEOPLASMS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
PHENOLS
PHOSPHATES
PHOSPHORUS COMPOUNDS
POLYPHENOLS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SYNTHESIS
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TECHNETIUM PHOSPHATES
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES