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Tantalum-178 - a short-lived nuclide for nuclear medicine: production of the parent W-178

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:6477314
The physical decay characteristics of the short-lived radionuclide Ta-178 (half-life 9.3 min) appear to be suitable for use in conjunction with low-energy detection systems such as the multiwire proportional camera. This camera is inefficient for emissions with energies greater than 100 keV. The gamma-ray spectrum of Ta-178 is dominated by the characteristic hafnium x-rays (55 to 65 keV), emitted as a result of electron-capture decay. The parent nuclide, W-178 (half-life 21.7 d), was produced in the Michigan State University cyclotron by proton bombardment of stacked natural tantalum-foil targets. Optimum production was found to occur with an incident proton energy of 34 MeV at an effective activity of 1.1 mCi/..mu..A-hr per MeV of target thickness. Tungsten-178 was chemically separated from the Ta foils with a yield of 98%.
Research Organization:
Harvard Medical School, Boston, MA
OSTI ID:
6477314
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 19:5; ISSN JNMEA
Country of Publication:
United States
Language:
English