Atomic and molecular physics in the gas phase
The spatial and temporal distributions of energy deposition by high-linear-energy-transfer radiation play an important role in the subsequent chemical and biological processes leading to radiation damage. Because the spatial structures of energy deposition events are of the same dimensions as molecular structures in the mammalian cell, direct measurements of energy deposition distributions appropriate to radiation biology are infeasible. This has led to the development of models of energy transport based on a knowledge of atomic and molecular interactions process that enable one to simulate energy transfer on an atomic scale. Such models require a detailed understanding of the interactions of ions and electrons with biologically relevant material. During the past 20 years there has been a great deal of progress in our understanding of these interactions; much of it coming from studies in the gas phase. These studies provide information on the systematics of interaction cross sections leading to a knowledge of the regions of energy deposition where molecular and phase effects are important and that guide developments in appropriate theory. In this report studies of the doubly differential cross sections, crucial to the development of stochastic energy deposition calculations and track structure simulation, will be reviewed. Areas of understanding are discussed and directions for future work addressed. Particular attention is given to experimental and theoretical findings that have changed the traditional view of secondary electron production for charged particle interactions with atomic and molecular targets.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 6476545
- Report Number(s):
- PNL-SA-18535; CONF-9009267-4; ON: DE91004811; TRN: 91-000376
- Resource Relation:
- Conference: Physical and chemical mechanisms in molecular radiation biology conference, Woods Hole, MA (USA), 3-7 Sep 1990
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
74 ATOMIC AND MOLECULAR PHYSICS
ELECTRON-MOLECULE COLLISIONS
IONIZATION
ION-ATOM COLLISIONS
ION-MOLECULE COLLISIONS
DIFFERENTIAL CROSS SECTIONS
DNA
ENERGY ABSORPTION
ENERGY LOSSES
ENERGY TRANSFER
HELIUM
IONIZING RADIATIONS
MOLECULAR BIOLOGY
NEON
NITROGEN
PHYSICAL RADIATION EFFECTS
WATER
ABSORPTION
ATOM COLLISIONS
COLLISIONS
CROSS SECTIONS
ELECTRON COLLISIONS
ELEMENTS
FLUIDS
GASES
HYDROGEN COMPOUNDS
ION COLLISIONS
LOSSES
MOLECULE COLLISIONS
NONMETALS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
RADIATION EFFECTS
RADIATIONS
RARE GASES
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