Hyperbaric oxygen in the treatment of osteoradionecrosis: a review of its use and efficacy

Journal Article · Sun Mar 01 04:00:00 EST 1987 · Oral Surg., Oral Med., Oral Pathol.; (United States)

DOI:https://doi.org/10.1016/0030-4220(87)90190-3· OSTI ID:6466661

Fattore, L; Strauss, R A

Hyperbaric oxygen (HBO) therapy is an established technology that is proving to be effective in the treatment of osteoradionecrosis. However, the studies that have shown this treatment modality to be effective have not established the optimum pressures, times of exposure, and frequency and number of treatment necessary for healing. In addition, most of the studies used HBO as an adjunctive treatment in the management of refractory osteoradionecrosis. The efficacy of HBO as a primary treatment modality has not as yet been established. Strictly controlled clinical trials are necessary for identification of patients who are likely to respond to HBO without aggressive surgery, to delineate a timetable for treatment of patients with HBO, and to coordinate surgery with HBO to resolve osteoradionecrosis when a significant amount of bone loss is involved.

• Research Organization: Univ. of Chicago, IL
• OSTI ID: 6466661
• Journal Information: Oral Surg., Oral Med., Oral Pathol.; (United States), Journal Name: Oral Surg., Oral Med., Oral Pathol.; (United States) Vol. 3; ISSN OSOMA
• Country of Publication: United States
• Language: English

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560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BODY
BONE TISSUES
CONNECTIVE TISSUE
DISEASES
ELEMENTS
HEALING
INJURIES
LOCAL RADIATION EFFECTS
NECROSIS
NONMETALS
OSTEORADIONECROSIS
OXYGEN
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATION INJURIES
RECOVERY
SKELETAL DISEASES
THERAPY
TISSUES
WOUNDS