Phase studies of a urethane model compound and polyether macroglycols by infrared spectroscopy and the relationship between eutectic composition of soft segment and blood compatibility

Journal Article · Thu Apr 01 04:00:00 EST 1993 · Journal of Biomedical Materials Research; (United States)

DOI:https://doi.org/10.1002/jbm.820270415· OSTI ID:6466272

Isama, Kazuo; Kojima, Shigeo; Nakamura, Akitada ^[1]

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1. National Inst. of Hygienic Sciences, Tokyo (Japan)

The binary mixtures of a urethane model compound, diethyl 4,4[prime]-methylenebis(N-phenylcarbamate) (MDU), and various polyether macroglycols have been investigated mainly by infrared (IR) spectroscopy. The mixtures of macroglycol and MDU showed two C=O bands and the intensity of free C=O increased while that of hydrogen bonded C=O decreased linearly with increasing molar ratio of macroglycol/MDU. The slope of the increase or decrease suddenly changed at the specific molar ratio around the eutectic composition. The eutectic molar composition for PTMO1000/MDU was determined as 1.15 or 1.1 by differential scanning calorimetry (DSC) or infrared (IR) studies while that for PTMO3000/MDU as 0.345 or 0.55 by DSC or IR, respectively. The eutectic compositions for other sets were determined by IR studies as follows: PEO1000/MDU, 0.4; PEO3000/MDU, 0.16; PPO1000/MDU, 1.4; PPO3000/MDU, 0.45. The number of ethylene oxide, tetramethylene oxide, and propylene oxide units to form a eutectic with MDU calculated from these values were 15-20, 10-11, and 23-24, respectively. The similar DSC or IR changes were observed in the various kinds of polyurethanes such as MDI/BD, MDI/PTMO/BD, and MDI/PTMO polymers. The relationship between the eutectic compositions of soft segments (MDI/macroglycol) and the ideal M[sub n] of the macroglycols in blood compatibility of segmented polyurethanes are discussed.

• OSTI ID: 6466272
• Journal Information: Journal of Biomedical Materials Research; (United States), Journal Name: Journal of Biomedical Materials Research; (United States) Vol. 27:4; ISSN 0021-9304; ISSN JBMRBG
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADHESION
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHEMICAL COMPOSITION
ERYTHROCYTES
INFRARED SPECTRA
MATERIALS
ORGANIC COMPOUNDS
ORGANIC POLYMERS
PETROCHEMICALS
PETROLEUM PRODUCTS
PHASE STUDIES
PHYSICAL PROPERTIES
PLASTICS
POLYAMIDES
POLYMERS
POLYURETHANES
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SYNTHETIC MATERIALS
TOXICITY