Conservation of bladder function in patients with invasive bladder cancer treated by definitive irradiation and selective cystectomy. [/sup 60/Co]

Journal Article · Fri May 01 04:00:00 EDT 1981 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(81)90367-9· OSTI ID:6460147

Goodman, G B ^[1]; Hislop, T G; Elwood, J M; Balfour, J

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1. A. Maxwell Evans Clinic, Vancouver, British Columbia

Four hundred seventy patients with invasive bladder cancer treated by definitive irradiation (5000 rad or more) and selective cystectomy were followed to assess their survival status and bladder function status. The survival rates for these patients were similar to those obtained in studies of preoperative irradiation with compulsory cystectomy. Sixty-five to 70% of these survivors lived with healthy, functioning bladders to at least 10 years after treatment. Seventy-five patients had a selective cystectomy, usually for recurrent disease, with an operative mortality rate of 11%. Therefore, definitive irradiation with selective cystectomy warrants serious consideration in treating patients with invasive bladder cancer, especially considering the quality of life and the high proportion of patients who retain functioning bladders.

• OSTI ID: 6460147
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 7:5; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
COBALT 60
COBALT ISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
THERAPY
URINARY TRACT
YEARS LIVING RADIOISOTOPES