New long-wavelength Nd:YAG laser at 1. 44 micron: effect on brain
Journal Article
·
· J. Neurosurg.; (United States)
A wavelength-shifted Nd:YAG laser, tuned to coincide with the infrared absorption peak of water at 1.44 microns, was used to make lesions in normal rabbit brain. A total of 48 lesions were made with power up to 20 W, with energy up to 40 joules, and with two different spot sizes. These lesions were compared to lesions made with 1.06 microns radiation from an Nd:YAG laser under identical operating conditions. Measurements of blood-brain barrier damage and width, depth, and volume of tissue affected were obtained 30 minutes after placement of the lesions. It was found that 1.44-microns lesions produced photoevaporative tissue loss at the highest intensities used. The layer of coagulated tissue remaining after photovaporization had a mean thickness of 0.6 mm irrespective of the volume of tissue removed. There was no photovaporization in the 1.06-microns lesions. In addition, the amount of peripheral edema per unit volume of tissue coagulated was approximately half at the 1.44-microns wavelength. These findings suggest that the 1.44-microns Nd:YAG laser may be a useful surgical instrument since it combines the photoevaporative effect of the CO/sub 2/ laser while maintaining the advantages of the conventional Nd:YAG laser (quartz fiber delivery and effective hemostasis).
- Research Organization:
- Univ. of Alberta, Edmonton (Canada)
- OSTI ID:
- 6458843
- Journal Information:
- J. Neurosurg.; (United States), Journal Name: J. Neurosurg.; (United States) Vol. 70:2; ISSN JONSA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Effects at the periphery of the laser lesion in human brain and its tumors after CO/sub 2/, Nd:YAG, and CO/sub 2/ high-peak pulsed radiation
Comparative investigations of the effects of the neodymium:YAG laser at 1. 06 microns and 1. 32 microns on tissue
Time course and spatial distribution of neodymium: yttrium-aluminum-garnet (Nd:YAG) laser-induced lesions in the rat brain
Journal Article
·
Tue Dec 31 23:00:00 EST 1985
· Lasers Surg. Med.; (United States)
·
OSTI ID:5112365
Comparative investigations of the effects of the neodymium:YAG laser at 1. 06 microns and 1. 32 microns on tissue
Journal Article
·
Wed Dec 31 23:00:00 EST 1986
· Lasers Surg. Med.; (United States)
·
OSTI ID:6350420
Time course and spatial distribution of neodymium: yttrium-aluminum-garnet (Nd:YAG) laser-induced lesions in the rat brain
Journal Article
·
Sun Mar 31 23:00:00 EST 1985
· Neurosurgery; (United States)
·
OSTI ID:5241141
Related Subjects
550600 -- Medicine
560400* -- Other Environmental Pollutant Effects
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BLOOD-BRAIN BARRIER
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
EDEMA
ELECTROMAGNETIC RADIATION
LASER RADIATION
LASERS
MAMMALS
MEDICINE
NEODYMIUM LASERS
NERVOUS SYSTEM
ORGANS
PATHOLOGICAL CHANGES
RABBITS
RADIATIONS
SOLID STATE LASERS
SURGERY
SYMPTOMS
VERTEBRATES
WAVELENGTHS
560400* -- Other Environmental Pollutant Effects
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BLOOD-BRAIN BARRIER
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
EDEMA
ELECTROMAGNETIC RADIATION
LASER RADIATION
LASERS
MAMMALS
MEDICINE
NEODYMIUM LASERS
NERVOUS SYSTEM
ORGANS
PATHOLOGICAL CHANGES
RABBITS
RADIATIONS
SOLID STATE LASERS
SURGERY
SYMPTOMS
VERTEBRATES
WAVELENGTHS