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Sensitivity of chest radiography, computed tomography, and gallium scanning to metastasis of lung carcinoma

Journal Article · · Cancer (Philadelphia); (United States)
; ; ; ; ; ;
To determine the efficacy of radiologic techniques in preoperative staging of the mediastinum for lung carcinoma, the authors studied 45 patients with chest films supplemented with oblique views, esophagrams, gallium scans, and computed tomograms (CT). They interpreted the studies and correlated surgical findings using a modified classification of lymph node regions. The mediastinum was positive on chest films in 14 of the 21 cases with pathologically proved mediastinal metastases (33% false-negative). Gallium scans in cases with a positive primary were positive in 12 of 15 cases with mediastinal or hilar metastases (20% false-negative). Computed tomography showed nodes over 1 or 1.5 cm in size in or adjacent to the biopsy-positive node region in 18 of 19 patients (5% false-negative), extranodal mediastinal involvement, and 9 of 10 proven hilar metastases. Computed tomography is a sensitive screening technique in patients who would otherwise require an invasive staging procedure, but is not highly specific (false-positive rate 38%).
Research Organization:
Departments of Radiology, Veteran's Administration Medical Center, La Jolla, California
OSTI ID:
6451191
Journal Information:
Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 54:7; ISSN CANCA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCURACY
BIOMEDICAL RADIOGRAPHY
BODY
BODY AREAS
CARCINOMAS
CHEST
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELEMENTS
GALLIUM
LUNGS
MEDIASTINUM
MEDICINE
METALS
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOLOGY
RESPIRATORY SYSTEM
TOMOGRAPHY