Radiation management of carcinoma of the tonsillar region
This is a retrospective analysis of 185 patients with squamous cell carcinoma of the tonsillar region treated at the Department of Radiation Oncology, University of Maryland Hospital from 1956 to 1977. All patients were treated by one of the following: (1) external beam therapy alone; or (2) combined external beam and interstitial brachytherapy. Five-year disease-free survivals, for early Stages (I and II), are 100% and 73%, comparable to the other series published in the literature. However, in advanced Stages III and IV, survival data showed 52% and 21%, respectively, 5-year disease-free survival better than any other reports. It is thought that the special interest of the authors in interstitial brachytherapy and a well-integrated plan of external beam and brachytherapy is responsible for this success. The local control rate for T1, T2, T3, and T4 was 94%, 88%, 62%, and 19%, respectively, with the overall regional control rate of 83%. The prognostic factors appear to be related to the T-factor, N-factor, radiation dose, and method of treatment given, and the degree of tongue involvement. The detailed analysis of survivals and failures in the light of dosimetric study is presented along with some example cases of interstitial brachytherapy.
- Research Organization:
- Department of Radiation Oncology, University of Maryland Hospital, Baltimore
- OSTI ID:
- 6449064
- Journal Information:
- Cancer (Philadelphia); (United States), Vol. 54:7
- Country of Publication:
- United States
- Language:
- English
Similar Records
Place of brachytherapy in the treatment of carcinoma of the tonsil with lingual extension
Brachytherapy as part of the definitive management of squamous cancer of the base of tongue
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
RADIOTHERAPY
DOSE-RESPONSE RELATIONSHIPS
PATIENTS
PHARYNX
SIDE EFFECTS
SURVIVAL TIME
TONGUE
BODY
DIGESTIVE SYSTEM
DISEASES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORAL CAVITY
ORGANS
RADIOLOGY
RESPIRATORY SYSTEM
THERAPY
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)