Suppression of analyte signal by various concomitant salts in inductively coupled plasma mass spectrometry

Journal Article · Wed Jan 01 04:00:00 EST 1986 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00292a008· OSTI ID:6445460

Olivares, J A; Houk, R S

The interference on the ionization of cobalt by five salts, NaCl, MgCl/sub 2/, NH/sub 4/I, NH/sub 4/Br, and NH/sub 4/Cl, in an inductively coupled plasma (ICP) is first looked at theoretically, and subsequently the theoretical trends are established experimentally by mass spectrometry (ICP-MS). The interference trends are found to be in the order of the most easily ionized element in the matrix salt, i.e., Na > Mg > I > Br > Cl. Quantitatively the theoretical values for the amount of salt needed to produce a particular interference are 1-2 orders of magnitude higher than the experimentally determined values. The results reported here indicate that ICP-MS is somewhat more susceptible to ionization suppression effects than ICP atomic emission spectrometry. It is also found that the most easily ionized element in the salt dominates the matrix ion spectrum observed from the ICP in the order mentioned above. Total ion current measurements by ICP-MC at solute levels above 1% are complicated by orifice plugging and transport loss of the salt and analyte in the desolvation system for the ultrasonic nebulizer used. 27 references, 7 figures, 3 tables.

• Research Organization: Iowa State Univ., Ames
• DOE Contract Number: W-7405-ENG-82
• OSTI ID: 6445460
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 58:1; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400104* -- Spectral Procedures-- (-1987)
ALKALI METAL COMPOUNDS
ALKALINE EARTH METAL COMPOUNDS
AMMONIUM COMPOUNDS
AMMONIUM HALIDES
CATIONS
CHARGED PARTICLES
CHEMICAL ANALYSIS
CHLORIDES
CHLORINE COMPOUNDS
COBALT COMPOUNDS
DATA
EXPERIMENTAL DATA
HALIDES
HALOGEN COMPOUNDS
INFORMATION
INTERFERENCE
ION SOURCES
IONS
MAGNESIUM CHLORIDES
MAGNESIUM COMPOUNDS
MASS SPECTROSCOPY
NUMERICAL DATA
PLASMA
QUANTITATIVE CHEMICAL ANALYSIS
QUANTITY RATIO
SIGNAL-TO-NOISE RATIO
SODIUM CHLORIDES
SODIUM COMPOUNDS
SPECTROSCOPY
TRANSITION ELEMENT COMPOUNDS