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Title: Ultrasonic characterization of single drops of liquids

Patent ·
OSTI ID:644439

Ultrasonic characterization of single drops of liquids is disclosed. The present invention includes the use of two closely spaced transducers, or one transducer and a closely spaced reflector plate, to form an interferometer suitable for ultrasonic characterization of droplet-size and smaller samples without the need for a container. The droplet is held between the interferometer elements, whose distance apart may be adjusted, by surface tension. The surfaces of the interferometer elements may be readily cleansed by a stream of solvent followed by purified air when it is desired to change samples. A single drop of liquid is sufficient for high-quality measurement. Examples of samples which may be investigated using the apparatus and method of the present invention include biological specimens (tear drops; blood and other body fluid samples; samples from tumors, tissues, and organs; secretions from tissues and organs; snake and bee venom, etc.) for diagnostic evaluation, samples in forensic investigations, and detection of drugs in small quantities. 5 figs.

Research Organization:
Univ. of California (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
W-7405-ENG-36
Assignee:
Univ. of California, Los Alamos, NM (United States)
Patent Number(s):
US 5,739,432/A/
Application Number:
PAN: 8-657,709
OSTI ID:
644439
Resource Relation:
Other Information: PBD: 14 Apr 1998
Country of Publication:
United States
Language:
English