Uptake and fate of phenol and aniline in rainbow trout and daphnids during single-compound and complex-mixture exposures

Technical Report · Mon Oct 01 04:00:00 EDT 1984

DOI:https://doi.org/10.2172/6443167· OSTI ID:6443167

Dauble, D D; Riley, R G; Bean, R M; Lusty, E W; Hanf, Jr, R W

Studies were conducted of the potential for uptake and mobilization of phenol and aniline when presented as single compounds to the biouptake of these compounds within a complex water-soluble fraction (WSF) of a coal liquid. Estimated bioconcentration factors (BCF) of phenol-only exposures differed from BCFs obtained in the presence of the WSF. Differences in uptake could be due to competitive interactions among similar molecules for uptake and absorption, since phenolic compounds comprised nearly 90% of the soluble components in the complex mixture. Observed differences in unextractable /sup 14/C residues suggested selective binding of phenol or metabolites to trout tissue storage sites. Differences in potential for bioaccumulation of phenol in complex mixtures were not consistent with estimates of BCF as determined by measured octanol/water coefficient values. In contrast to phenol, presence of coal-liquid water solubles did not significantly influence either the uptake or elimination of /sup 14/C aniline by daphnids or trout. Identification of metabolites would provide useful information on potential differences in biotransformation and elimination mechanisms in complex organic mixtures. 15 references, 2 figures, 6 tables.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6443167
• Report Number(s): PNL-5264; ON: DE85002802
• Country of Publication: United States
• Language: English

Related Subjects

01 COAL, LIGNITE, AND PEAT
010900 -- Coal
Lignite
& Peat-- Environmental Aspects
560304 -- Chemicals Metabolism & Toxicology-- Invertebrates-- (-1987)
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ANILINE
ANIMALS
AQUATIC ORGANISMS
AROMATICS
ARTHROPODS
BRANCHIOPODS
CARBON 14 COMPOUNDS
CLEARANCE
COAL LIQUIDS
CRUSTACEANS
DAPHNIA
EXCRETION
FLUIDS
HYDROXY COMPOUNDS
INVERTEBRATES
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LIQUIDS
METABOLISM
METABOLITES
ORGANIC COMPOUNDS
PHENOL
PHENOLS
TRACER TECHNIQUES
UPTAKE