Effect of complexans (EDTA, NTA and DTPA) on the exposure to high concentrations of cadmium, copper, zinc and lead

Journal Article · Mon Dec 01 04:00:00 EST 1980 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01985635· OSTI ID:6441719

Muramoto, S

The effects of complexans on the toxicity of short exposures to high chemical concentrations of heavy meals were examined. The heavy metals used were cadmium, zinc, lead and copper. Mortality every 24-h and the content of metal in each of three areas of fish - viscera, gills and other parts - were detemined both in the groups kept in water containing metal alone and in those whose aqueous environments contained complexan in mole concentrations three time that of the heavy metal. The carp (Cyprinus carpio L.) 8.0 + 0.5 cm were kept in groups of 8 to 10. There were altogether 49 such groups: 12 kept in three relatively high concentrations of each of the metals, Cu, Cd, Pb and Zn, alone; 36 groups in environments each containing only one of the three complexans, the tetrasodium salt of ethylene-diamine tetraacetic acid (EDTA), the trisodium salt of nitrilotriacetic acid (NTA), and the pentasodium salt of diethylenetriamine pentaacetic acid (DTPA) were used. Results indicate that the addition of the complexans resulted in the decrease of the tissue concentrations of Cd, Zn, Pb and Cu. It is considered that the heavy metals were not present merely as metal ions but formed complexes with the complexans, since the complexans were added at three times mole of the metal and therefore complex formation occurred in preference to the binding of the metals with the tissue proteins of the fish. It is furthermore assumed that the heavy metals can pass through the fish as metal-complexes, and so are not retained.

• Research Organization: Okayama Univ., Kurashiki, Japan
• OSTI ID: 6441719
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 25:6; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL EFFECTS
BIOLOGICAL LOCALIZATION
CADMIUM
CARBOXYLIC ACIDS
CHELATING AGENTS
CLEANING
COPPER
DECONTAMINATION
DRUGS
DTPA
EDTA
ELEMENTS
FISHES
LEAD
METALS
MORTALITY
NTA
ORGANIC ACIDS
ORGANIC COMPOUNDS
RADIOPROTECTIVE SUBSTANCES
RESPONSE MODIFYING FACTORS
TOXICITY
TRANSITION ELEMENTS
VERTEBRATES
ZINC