The relationships between the Ga-67 uptake and nuclear DNA feulgen content in thyroid tumors: concise communication

Journal Article · Mon Nov 01 04:00:00 EST 1982 · J. Nucl. Med.; (United States)

OSTI ID:6437133

Higashi, T ^[1]; Watanabe, Y; Yamaguchi, M; Hisada, T; Mimura, T; Ito, K; Allison, J R

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1. Kanagawa Kental Coll., Yokosuka, Japan

It has been reported that Ga-67 uptake by malignant tumors differs somewhat according to the histologic type. Previously, we reported that uptake of Ga-67 is predictably low in well-differentiated adenocarcinoma of the thyroid gland but high in anaplastic carcinoma and malignant lymphoma. We studied the relationship between Ga-67 uptake and nuclear DNA content in four papillary adenocarcinomas, three follicular adenocarcinomas, three anaplastic carcinomas, and five malignant lymphomas of the thyroid gland. In anaplastic carcinoma and malignant lymphoma, the nuclear DNA content and proliferative index were significantly higher than in well-differentiated adenocarcinoma. These results suggest that there is close correlation between Ga-67 uptake and degree of malignancy of thyroid tumor cells.

• OSTI ID: 6437133
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 23:11; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CELL PROLIFERATION
CLASSIFICATION
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
DNA
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
FEULGEN METHOD
GALLIUM 67
GALLIUM ISOTOPES
GLANDS
INTERMEDIATE MASS NUCLEI
ISOTOPES
NEOPLASMS
NUCLEI
NUCLEIC ACIDS
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
THYROID
UPTAKE