Implications of the ICRP Task Group's proposed lung model for internal dose assessments in the mineral sands industry
- Pacific Northwest Lab., Richland, WA (USA)
- National Radiological Protection Board, Chilton (UK)
The ICRP Task Group on Respiratory Tract Models for Radiological Projection is proposing a model to describe the deposition, clearance, retention and dosimetry of inhaled radionuclides for dose-intake calculations and interpretation of bioassay data. The deposition model takes into account new data on the regional deposition of aerosol particles in human lung and the inhalability of large particles. The clearance model treats clearance as competition between mechanical transport, which moves particles to the gastro-intestinal tract and lymph nodes, and the translocation of material to blood. This provides a realistic estimate of the amount of a given material (such as mineral sand) that is absorbed systemically, and its variation with aerosol size. The proposed dosimetry model takes into account the relative sensitivities of the various tissue components of the respiratory tract. A new treatment of dose received by epithelia in the tracheo-bronchiolar and extrathoracic regions is proposed. This paper outlines the novel features of the task group model, and then examines the impact that adoption of the model may have on the assessment of doses from occupational exposures to mineral sands and thoron progeny. 39 refs., 15 figs., 6 tabs.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 6435157
- Report Number(s):
- PNL-SA-18595; CONF-9009305--1; ON: DE91004812
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE COMPOUNDS
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
AEROSOLS
ALPHA DECAY RADIOISOTOPES
ANIMAL TISSUES
BIOLOGICAL ACCUMULATION
BIOLOGICAL MODELS
BODY
CLEARANCE
COLLOIDS
DAUGHTER PRODUCTS
DISEASES
DISPERSIONS
DOSE EQUIVALENTS
DOSE RATES
DOSIMETRY
ELEMENTS
EPITHELIUM
EVEN-EVEN NUCLEI
EXCRETION
FLUIDS
GASES
HAZARDS
HEALTH HAZARDS
HEAVY NUCLEI
ICRP
INHALATION
INTAKE
INTERNATIONAL ORGANIZATIONS
ISOTOPES
LUNGS
MATERIALS
MINERALS
MONAZITES
NEOPLASMS
NONMETALS
NUCLEI
OCCUPATIONAL EXPOSURE
ORES
ORGANS
OXYGEN COMPOUNDS
PARTICLES
PHOSPHATES
PHOSPHORUS COMPOUNDS
RADIATION HAZARDS
RADIOACTIVE MATERIALS
RADIOACTIVE MINERALS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RADON
RADON 220
RADON ISOTOPES
RARE EARTH COMPOUNDS
RARE GASES
RESPIRATORY SYSTEM
SECONDS LIVING RADIOISOTOPES
SOLS
THORIUM 228
THORIUM 232
THORIUM COMPOUNDS
THORIUM ISOTOPES
THORIUM MINERALS
THORIUM ORES
THORIUM PHOSPHATES
TISSUES
YEARS LIVING RADIOISOTOPES