Abnormal gallium scan patterns of the salivary gland in pulmonary sarcoidosis
The findings of gallium imaging suggest that parotid abnormalities in sarcoidosis are common. Correlation with lung and mediastinal uptake suggests that this represents an early disease state and that it responds to steroid administration. That the findings after therapy do not simply represent suppression of the uptake mechanism for gallium is supported by objective improvement in pulmonary function as well as symptomatic relief. Salivary gland accumulation of gallium citrate occurred in one third of our control group patients--in those who had collagen disease and presumably either were alcoholic or had infectious parotitis. This may also be seen in lymphoma and after radiation therapy. Although the combination of salivary gland, pulmonary, and hilar concentration of gallium is not specific, in the appropriate clinical setting the pattern may be helpful in suggesting the correct diagnosis.
- Research Organization:
- Martin Luther King, Jr., General Hospital, Los Angeles, CA
- OSTI ID:
- 6433786
- Journal Information:
- Ann. Intern. Med.; (United States), Journal Name: Ann. Intern. Med.; (United States) Vol. 89:6; ISSN AIMEA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
GALLIUM ISOTOPES
GLANDS
IMAGES
LUNGS
ORGANS
RADIOISOTOPE SCANNING
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SALIVARY GLANDS
SCINTISCANNING
THERAPY
UPTAKE