Evaluation of the potential carcinogenicity of aziridine. Final report
Technical Report
·
OSTI ID:6428443
Aziridine is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is No Data. The potency factor (F) for aziridine is estimated to be 336 (mg/kg/day)(-1), placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, aziridine is assigned a HIGH hazard ranking for the purposes of RQ adjustment.
- Research Organization:
- Syracuse Research Corp., NY (United States)
- OSTI ID:
- 6428443
- Report Number(s):
- PB-93-184919/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
29 ENERGY PLANNING, POLICY, AND ECONOMY
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOGENS
DATA PROCESSING
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
MATERIALS
NATIONAL ORGANIZATIONS
NEOPLASMS
PHYSIOLOGY
PROCESSING
PUBLIC HEALTH
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOGENS
DATA PROCESSING
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
MATERIALS
NATIONAL ORGANIZATIONS
NEOPLASMS
PHYSIOLOGY
PROCESSING
PUBLIC HEALTH
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT