Enriched isotope applications: biomedical field. [New stable isotopes for clinical use and use in beomedical research]

Technical Report · Wed Apr 18 00:00:00 EST 1979

DOI:https://doi.org/10.2172/6425705· OSTI ID:6425705

DeWitt, R

The recognized need for high purity radionuclides and the need for organ specific radiopharmaceuticals will stimulate the demand for large quantities of stable isotopes. Stable isotopes currently under investigation for use as targets for radionuclide production include: /sup 95/ /sup 98/ /sup 100/Mo, /sup 203/ /sup 205/Tl, /sup 201/Hg, /sup 66/ /sup 67/Zn, /sup 122/ /sup 123/Te, /sup 112/Sn, /sup 111/ /sup 112/Cd, /sup 50/Cr, /sup 50/V, /sup 82/Kr, /sup 197/Au, /sup 72/ /sup 74/Ge, /sup 54/ /sup 58/Fe, /sup 63/Cu, /sup 64/Ni, /sup 69/Ga, /sup 43/ /sup 46/Ca, /sup 41/K, /sup 35/Cl, /sup 23/Na, /sup 81/Br, /sup 84/Sr, /sup 85/Rb, /sup 75/As, /sup 76/Se, /sup 81/Br, /sup 31/P, /sup 29/Si, /sup 156/Dy, /sup 152/Sm, /sup 170/Er, /sup 175/Lu, /sup 178/Lu, /sup 168/Yb, /sup 11/B, /sup 14/N, /sup 16/O, /sup 20/Ne, and /sup 124/Xe. As isotope production and radiopharmaceutical preparation costs are lowered and FDA approvals are secured, increased demand could develop for most of the stable isotopes listed. Requirements appear to be increasing for isotopes of those elements which are considered biologically essential (currently 25 elements) or for those which have an effect on the life processes. Demand is currently developing for the isotopes of the elements; K, Ca, Mg, Fe, Cu, Zn, Ni, Cd, and Cr. High isotope costs, however, and the scarcity of some metal isotopes have severely limited biomedical research programs. (ERB)

• Research Organization: Mound Plant (MOUND), Miamisburg, OH (United States)
• DOE Contract Number: EY-76-C-04-0053
• OSTI ID: 6425705
• Report Number(s): MLM-2593; TRN: 79-010877
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
BIOCHEMISTRY
ISOTOPE APPLICATIONS
BIOLOGY
MEDICINE
NUCLEAR MEDICINE
PHYSIOLOGY
RADIOPHARMACEUTICALS
CHEMICAL PREPARATION
STABLE ISOTOPES
DIAGNOSTIC USES
ISOTOPE PRODUCTION
USES
ARSENIC 75
BORON 11
BROMINE 81
CADMIUM 111
CADMIUM 112
CALCIUM 43
CALCIUM 46
CHLORINE 35
CHROMIUM 50
COPPER 63
DYSPROSIUM 156
ERBIUM 170
GALLIUM 69
GERMANIUM 72
GERMANIUM 74
GOLD 197
IRON 54
IRON 58
KRYPTON 82
LUTETIUM 175
LUTETIUM 178
MERCURY 201
MOLYBDENUM 100
MOLYBDENUM 95
MOLYBDENUM 98
NEON 20
NICKEL 64
NITROGEN 14
OXYGEN 16
PHOSPHORUS 31
POTASSIUM 41
RUBIDIUM 85
SAMARIUM 152
SELENIUM 76
SILICON 29
SODIUM 23
STRONTIUM 84
TELLURIUM 122
TELLURIUM 123
THALLIUM 203
THALLIUM 205
TIN 112
VANADIUM 50
XENON 124
YTTERBIUM 168
ZINC 66
ZINC 67
ALKALI METAL ISOTOPES
ALKALINE EARTH ISOTOPES
ARSENIC ISOTOPES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BORON ISOTOPES
BROMINE ISOTOPES
CADMIUM ISOTOPES
CALCIUM ISOTOPES
CHEMISTRY
CHLORINE ISOTOPES
CHROMIUM ISOTOPES
COPPER ISOTOPES
DAYS LIVING RADIOISOTOPES
DRUGS
DYSPROSIUM ISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
ERBIUM ISOTOPES
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
GALLIUM ISOTOPES
GERMANIUM ISOTOPES
GOLD ISOTOPES
HEAVY NUCLEI
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRON ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KRYPTON ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
LUTETIUM ISOTOPES
MERCURY ISOTOPES
MINUTES LIVING RADIOISOTOPES
MOLYBDENUM ISOTOPES
NEON ISOTOPES
NICKEL ISOTOPES
NITROGEN ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
OXYGEN ISOTOPES
PHOSPHORUS ISOTOPES
POTASSIUM ISOTOPES
RADIOACTIVE MATERIALS
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
RUBIDIUM ISOTOPES
SAMARIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
SELENIUM ISOTOPES
SILICON ISOTOPES
SODIUM ISOTOPES
STRONTIUM ISOTOPES
SYNTHESIS
TELLURIUM ISOTOPES
THALLIUM ISOTOPES
TIN ISOTOPES
VANADIUM ISOTOPES
XENON ISOTOPES
YEARS LIVING RADIOISOTOPES
YTTERBIUM ISOTOPES
ZINC ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550201 - Biochemistry- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques
400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials
400703 - Radiochemistry & Nuclear Chemistry- Radioisotope Production