Dual radiopharmaceutical imaging in congenital asplenia syndrome

Journal Article · Wed Dec 01 04:00:00 EST 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.145.3.7146415· OSTI ID:6422380

Rao, B K; Shore, R M; Lieberman, L M; Polcyn, R E

Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood smears. /sup 99m/Tc-sulfur colloid scans were equivocal for absence of the spleen. When they were compared with the /sup 99m/Tc-PIPIDA hepatobiliary images, a discrepancy in organ morphology between the two scans indicated that the spleen was present, whereas similarity of the two images suggested asplenia. This procedure was useful in establishing asplenia in 4 patients and confirming the presence of a rudimentary or ectopic spleen in 2 others. Unequivocal demonstration of the spleen on the sulfur colloid scans makes the hepatobiliary study unnecessary, while unequivocal demonstration of a normal-appearing liver without splenic activity may warrant a tagged red-cell study for a more complete evaluation.

• Research Organization: Department of Radiology, University Hospital, Cleveland, Ohio
• OSTI ID: 6422380
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 145:3; ISSN RADLA
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COLLOIDS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
DISPERSIONS
ERYTHROCYTES
HEMIC DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MORPHOLOGY
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOCOLLOIDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SPLEEN
TECHNETIUM 99
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES