Reduction of mercuric ion and exhalation of mercury in acatalasemic and normal mice

Journal Article · · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1987.9935791· OSTI ID:6406977

Ogata, M; Kenmotsu, K; Aikoh, H

A significant difference in the amount of exhaled mercury per hour between normal and acatalasemic mice was observed in 7 of 11 experiments for different periods of time. The total amount of mercury exhaled from acatalasemic mice was significantly higher than those of normal mice. The results confirm that the reduction of mercuric ion to metallic mercury occurs by recycling of mercury in the tissues and reoxidized metallic mercury to mercuric ion by catalase. Mercuric ion was reduced to metallic mercury in the presence of superoxide anion in vitro. The reduction rate of mercuric ion to metallic mercury in the presence of both superoxide anion and cytochrome C or nitro blue tetrazolium was higher than that in the presence of superoxide anion alone, and the reduction of mercuric ion by NADPH or NADH was also observed. The reduction of mercuric ion to metallic mercury by liver homogenates of acatalasemic mice was higher than that of normal mice.

• Research Organization: Okayama Univ. Medical School, Okayama City, Japan
• OSTI ID: 6406977
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 42:1; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BODY
CATALASE
CHEMICAL REACTIONS
CLEARANCE
COENZYMES
DIGESTIVE SYSTEM
ELEMENTS
ENZYMES
EXCRETION
EXHALATION
GLANDS
HOMOGENATES
LIVER
MAMMALS
MERCURY
METABOLISM
METALS
MICE
NADH2
NADP
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANS
OXIDOREDUCTASES
PEROXIDASES
REDUCTION
RODENTS
VERTEBRATES