Simultaneous technetium-99m MIBI angiography and myocardial perfusion imaging

Journal Article · Sun Jan 01 04:00:00 EST 1989 · J. Nucl. Med.; (United States)

OSTI ID:6406731

Baillet, G Y; Mena, I G; Kuperus, J H; Robertson, J M; French, W J

Resting first-pass radionuclide angiography (FPRNA) was performed with the myocardial perfusion agent technetium-99m MIBI. In 27 patients, it was compared with technetium-99m diethylenetriamine pentaacetic acid FPRNA. A significant correlation was present in left (r = 0.93, p less than 0.001) as well as right (r = 0.92, p less than 0.001) ventricular ejection fraction measured with both radiopharmaceuticals. In 13 patients, MIBI derived segmental wall motion was compared with contrast ventriculography. A high correlation was present (p less than 0.001), and qualitative agreement was found in 38/52 segments. In 19 patients with myocardial infarction a significant correlation was present between MIBI segmental wall motion and perfusion scores (p less than 0.001). In ten patients with a history of myocardial infarction, 18 myocardial segments demonstrated diseased coronary vessels and impaired wall motion at contrast angiography. These segments were all identified by the MIBI wall motion and perfusion study. We conclude that MIBI is a promising agent for simultaneous evaluation of cardiac function and myocardial perfusion at rest.

• Research Organization: UCLA School of Medicine, Harbor-UCLA Medical Center, Torrance (USA)
• OSTI ID: 6406731
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 30:1; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
CARBOXYLIC ACIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CHELATING AGENTS
COMPARATIVE EVALUATIONS
CONTRAST MEDIA
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DTPA
HEART
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MEDICINE
MYOCARDIAL INFARCTION
NITRILES
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
PATIENTS
PERFUSED TISSUES
PROCESSING
RADIOISOTOPES
RADIOLOGY
RADIOPHARMACEUTICALS
RADIOPROTECTIVE SUBSTANCES
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES