Acute amaurotic epilepsy caused by lead poisoning in non-human primates

Journal Article · Fri Sep 15 04:00:00 EDT 1972 · J. Am. Vet. Med. Assoc.; (United States)

OSTI ID:6403271

Zook, B C; Sauer, R M; Garner, F M

Lead poisoning was diagnosed in all of 14 simian primates that died of acute amaurotic epilepsy at the National Zoological Park. Two primates from the Antwerp Zoo included in the original description of acute amaurotic epilepsy were also retrospectively found to have lead poisoning. Diagnosis was based on history, clinical signs, histologic brain lesions, available source of lead, acid-fast intranuclear inclusion bodies in renal and hepatic cells, and excess lead in liver specimens. It was concluded that acute amaurotic epilepsy should be considered a clinical syndrome of lead intoxication.

• Research Organization: George Washington Univ., Washington, DC
• OSTI ID: 6403271
• Journal Information: J. Am. Vet. Med. Assoc.; (United States), Journal Name: J. Am. Vet. Med. Assoc.; (United States) Vol. 161:6; ISSN JAVMA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
DEATH
ELEMENTS
LEAD
MACACUS
MAMMALS
METALS
MONKEYS
PRIMATES
TOXICITY
VERTEBRATES