Arsenic toxicity in cattle
Results indicate that in the cow, arsenic acid is absorbed and excreted rapidly in the urine. As a result, there is little storage in the tissues, and these low levels are rapidly depleted in a feed-off period and represent ''transit'' rather than true storage arsenic. Preliminary studies show that this tissue-bound arsenic is entirely in the pentavalent form, and that there is no evidence that it is partially reduced to the trivalent form. At no time was there any arsenic excreted in the milk when fed arsenic acid, sodium arsenite, or cacodylic acid. The marked difference between the metabolism of arsenic in the rat and any other animal makes it necessary to revise present concepts of arsenic compounds as cumulative poisons. 8 references, 7 tables.
- Research Organization:
- Univ. of California, Davis
- OSTI ID:
- 6403167
- Journal Information:
- Ann. N.Y. Acad. Sci.; (United States), Vol. 111
- Country of Publication:
- United States
- Language:
- English
Similar Records
Tissue dosimetry, metabolism and excretion of pentavalent and trivalent dimethylated arsenic in mice after oral administration
Arsenic: potential hazards of environmental exposure
Related Subjects
ARSENIC
METABOLISM
TOXICITY
ARSENIC COMPOUNDS
BIOLOGICAL ACCUMULATION
BIOLOGICAL EFFECTS
COWS
EXCRETION
EXPERIMENTAL DATA
FEEDING
MILK
RATS
TISSUES
ANIMALS
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CATTLE
CLEARANCE
DATA
DOMESTIC ANIMALS
ELEMENTS
FOOD
INFORMATION
MAMMALS
MATERIALS
NUMERICAL DATA
RODENTS
RUMINANTS
SEMIMETALS
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)