Microwave effects on plasmid DNA

Journal Article · Fri May 01 00:00:00 EDT 1987 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3576900· OSTI ID:6402982

Sagripanti, J L; Swicord, M L; Davis, C C

The exposure of purified plasmid DNA to microwave radiation at nonthermal levels in the frequency range from 2.00 to 8.75 GHz produces single- and double-strand breaks that are detected by agarose gel electrophoresis. Microwave-induced damage to DNA depends on the presence of small amounts of copper. This effect is dependent upon both the microwave power and the duration of the exposure. Cuprous, but not cupric, ions were able to mimic the effects produced by microwaves on DNA.

• Research Organization: Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD
• OSTI ID: 6402982
• Journal Information: Radiat. Res.; (United States), Vol. 2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DNA
STRAND BREAKS
MICROWAVE RADIATION
GENETIC EFFECTS
COPPER
ELECTROPHORESIS
PLASMIDS
BIOLOGICAL EFFECTS
CELL CONSTITUENTS
ELECTROMAGNETIC RADIATION
ELEMENTS
METALS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
RADIATIONS
TRANSITION ELEMENTS
560400* - Other Environmental Pollutant Effects