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Effect of pore diffusion in enantioselective hydrogenation with supported nickel catalysts

Journal Article · · J. Catal.; (United States)
Nickel dispersed on wide-pore silica has been used as catalyst in a study of the reaction kinetics of the hydrogenation of methyl-acetoacetate (MAA). The hydrogenation in the gas phase with a H/sub 2//MAA ratio of approx. 10/sup 3/ is found to be limited by the catalytic reaction proper if the rate is kept low, but tends to become limited by pore diffusion of MAA when higher temperatures, higher Ni surface areas, or lower space velocities are used. In the liquid (MAA + methanol) phase the rate is limited by pore diffusion of dissolved hydrogen. Consequently the rate depends on the catalyst pellet size, as does also the enantioselectivity for samples modified with aqueous R,R-tartaric acid.
Research Organization:
Rijksuniversiteit Leiden, Netherland
OSTI ID:
6384337
Journal Information:
J. Catal.; (United States), Journal Name: J. Catal.; (United States) Vol. 76:2; ISSN JCTLA
Country of Publication:
United States
Language:
English