Effect of low-level carbon monoxide exposure on onset and duration of angina pectoris

Journal Article · Sun Dec 31 23:00:00 EST 1972 · Ann. Intern. Med.; (United States)

DOI:https://doi.org/10.7326/0003-4819-79-1-46· OSTI ID:6380462

Anderson, E W; Andelman, R J; Strauch, J M; Fortuin, N J; Knelson, J H

Ten volunteers with ischemic heart disease (stable angina) were exposed in a double-blind experiment to 0, 50, or 100 ppM CO for 4 hr prior to treadmill exercise. COHb averaged 1.3, 2.9, and 4.5% just after exposure. CO decreased exercise time to anginal pain and prolonged duration of pain after stopping exercise. 5 of 10 had deeper ST-segment depression.

• OSTI ID: 6380462
• Journal Information: Ann. Intern. Med.; (United States), Journal Name: Ann. Intern. Med.; (United States) Vol. 79; ISSN AIMEA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL STRESS
BODY
CARBON COMPOUNDS
CARBON MONOXIDE
CARBON OXIDES
CARBOXYHEMOGLOBIN
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CHALCOGENIDES
DISEASES
EXERCISE
HEART
MAMMALS
MAN
ORGANS
OXIDES
OXYGEN COMPOUNDS
PRIMATES
VERTEBRATES