Autoradiography for iodine-125 seeds

Journal Article · Thu Apr 01 23:00:00 EST 1993 · International Journal of Radiation Oncology, Biology and Physics; (United States)

DOI:https://doi.org/10.1016/0360-3016(93)90319-Q· OSTI ID:6375487

Alberti, W; Divoux, S ^[1]; Pothmann, B; Tabor, P ^[2]; Hermann, K P; Harder, D ^[3]

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1. Alfried Krupp Krankenhaus, Essen (Germany)
2. Universitaetsklinikum, Essen (Germany)
3. Universitaet Goettingen (Germany)

To study the interior design of model 6702 and 6711 iodine-125 seeds, contact autoradiographs were performed using mammography film. Improved resolution was obtained using a pin-hole camera with a hole of 0.1 mm [times] 0.1 mm. With these techniques, qualitative determination of the relative activity distribution within each seed was possible. The number of the activated resin spheres and the positions of the centers of these spheres can be exactly determined. A model calculation shows that variations in the arrangement of the activated spheres within a seed have a moderate influence on the dose distribution at source distances below 10 mm. Knowing the exact source configuration may be useful when comparing dose calculations with measured data for model 6702 [sup 125]I seeds which are currently employed in ophthalmic plaque and implant therapy of other tumors. 16 refs., 5 figs., 2 tabs.

• OSTI ID: 6375487
• Journal Information: International Journal of Radiation Oncology, Biology and Physics; (United States), Journal Name: International Journal of Radiation Oncology, Biology and Physics; (United States) Vol. 25:5; ISSN IOBPD3; ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560101 -- Biomedical Sciences
Applied Studies-- Radiation Effects-- Dosimetry & Monitoring-- (1992-)
61 RADIATION PROTECTION AND DOSIMETRY
62 RADIOLOGY AND NUCLEAR MEDICINE
AUTORADIOGRAPHY
BETA DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
DISTRIBUTION
ELECTRON CAPTURE RADIOISOTOPES
IMPLANTS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IODINE 125
IODINE ISOTOPES
ISOTOPES
MATHEMATICAL MODELS
MEDICINE
MICROSPHERES
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
RADIATION DOSE DISTRIBUTIONS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SPATIAL DISTRIBUTION
SPATIAL DOSE DISTRIBUTIONS
THERAPY