Esophagitis induced by combined radiation and adriamycin. [Mediastinum irradiated to doses between 500 and 2500 rad]
Journal Article
·
· Am. J. Roentgenol.; (United States)
With the increasing use of combined chemotherapy and radiotherapy in the treatment of certain types of malignancy, a clinically distinct type of esophagitis has been recognized as an undesirable side effect. It occurs with low doses (less than 2,000 rad) of mediastinal radiation in patients who simultaneously or sequentially receive either adriamycin or actinomycin D. Characteristic of this entity is recall: recurrent episodes of esophagitis with each course of chemotherapy. The radiographic findings are nonspecific, ranging from subtle alterations in motility to severe damage with irreversible stricture formation. The primary differential diagnostic considerations are infectious processes. The radiographic spectrum clinical aspects, and differential diagnoses in five patients are discussed.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 6370633
- Journal Information:
- Am. J. Roentgenol.; (United States), Journal Name: Am. J. Roentgenol.; (United States) Vol. 132:4; ISSN AJROA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANTINEOPLASTIC DRUGS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEMOTHERAPY
CHEST
DIGESTIVE SYSTEM
DISEASES
DOSES
DRUGS
ESOPHAGUS
HEMIC DISEASES
INFLAMMATION
IONIZING RADIATIONS
IRRADIATION
LEUKEMIA
LOCAL IRRADIATION
LYMPHOMAS
MEDIASTINUM
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OSTEOSARCOMAS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
RADIOSENSITIVITY EFFECTS
RADIOTHERAPY
SARCOMAS
SIDE EFFECTS
SKELETAL DISEASES
THERAPY
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANTINEOPLASTIC DRUGS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEMOTHERAPY
CHEST
DIGESTIVE SYSTEM
DISEASES
DOSES
DRUGS
ESOPHAGUS
HEMIC DISEASES
INFLAMMATION
IONIZING RADIATIONS
IRRADIATION
LEUKEMIA
LOCAL IRRADIATION
LYMPHOMAS
MEDIASTINUM
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OSTEOSARCOMAS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
RADIOSENSITIVITY EFFECTS
RADIOTHERAPY
SARCOMAS
SIDE EFFECTS
SKELETAL DISEASES
THERAPY