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Measurement of. beta. -endorphin in human plasma. [/sup 131/I tracer technique]

Journal Article · · J. Clin. Endocrinol. Metab.; (United States)
..beta..-endorphin has been identified in human plasma by means of gel filtration and a sensitive radioimmunoasay for human ..beta..-endorphin (..beta../sub h/-endorphin). Mean baseline plasma ..beta../sub h/-endorphin concentration in 5 individuals was 21 +- 7.3 (SD) pg/ml (6.2 +- 2.2 (SD) fmole/ml). Following metyrapone stimulation mean plasma concentration increased to 55.4 +- 10.1 (SD) pg/ml (16.3 +- 3.1 (SD) fmole/ml). The molar ratio of human ..beta..-lipotropin (..beta../sub h/-LPH) to ..beta../sub h/-endorphin was 2.2 in baseline plasma and 2.4 after metyrapone stimulation.
Research Organization:
Columbia Univ., New York, NY
OSTI ID:
6368535
Journal Information:
J. Clin. Endocrinol. Metab.; (United States), Journal Name: J. Clin. Endocrinol. Metab.; (United States) Vol. 48:1; ISSN JCEMA
Country of Publication:
United States
Language:
English