Bone density of the radius, spine, and proximal femur in osteoporosis
Bone mineral density (BMD) was measured in 140 normal young women (aged 20 to 39 years) and in 423 consecutive women over age 40 referred for evaluation of osteoporosis. Lumbar spine and proximal femur BMD was measured using dual-photon absorptiometry (/sup 153/Gd), whereas the radius shaft measurement used single-photon absorptiometry (/sup 125/I). There were 324 older women with no fractures, of which 278 aged 60 to 80 years served as age-matched controls. There were 99 women with fractures including 32 with vertebral and 22 with hip fractures. Subsequently, another 25 women with hip fractures had BMD measured in another laboratory; their mean BMD was within 2% of that of the original series. The mean age in both the nonfracture and fracture groups was 70 +/- 5 years. The BMD in the age-matched controls was 20% to 25% below that of normal young women for the radius, spine, and femur, but the Ward's triangle region of the femur showed even greater loss (35%). The mean BMD at all sites in the crush fracture cases was about 10% to 15% below that of age-matched controls. Spinal abnormality was best discriminated by spine and femoral measurements (Z score about 0.9). In women with hip fractures, the BMD was 10% below that of age-matched controls for the radius and the spine, and the BMD for the femoral sites was about 25% to 30% below that of age-matched control (Z score about 1.6). Femoral densities gave the best discrimination of hip fracture cases and even reflected spinal osteopenia. In contrast, neither the spine nor the radius reflected the full extent of femoral osteopenia in hip fracture.
- Research Organization:
- Univ. of Wisconsin, Madison (USA)
- OSTI ID:
- 6352990
- Journal Information:
- J. Bone Miner. Res.; (United States), Vol. 3:1
- Country of Publication:
- United States
- Language:
- English
Similar Records
Osteoporosis in unstable adult scoliosis
Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes
Related Subjects
OSTEOPOROSIS
DIAGNOSIS
SKELETON
EMISSION COMPUTED TOMOGRAPHY
ARMS
BONE FRACTURES
DENSITY
FEMUR
GADOLINIUM 153
IODINE 125
MINERALS
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
VERTEBRAE
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
GADOLINIUM ISOTOPES
INJURIES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
LIMBS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHYSICAL PROPERTIES
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
SKELETAL DISEASES
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics