Tc-99m-DTPA aerosol and radioactive gases compared as adjuncts to perfusion scintigraphy in patients with suspected pulmonary embolism

Journal Article · Thu Nov 01 04:00:00 EST 1984 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.153.2.6385113· OSTI ID:6349731

Alderson, P O; Biello, D R; Gottschalk, A; Hoffer, P B; Kroop, S A; Lee, M E; Ramanna, L; Siegel, B A; Waxman, A D

To evaluate the clinical utility of improved methods for radioaerosol inhalation imaging, we obtained preperfusion radioaerosol images in 107 patients (mean age = 62 years), who were referred for evaluation of suspected pulmonary embolism (PE). For each patient, we compared six-view aerosol images with accompanying perfusion scans and chest radiographs and with Xenon-133 (Xe-133) or Krypton-81 m (Kr-81m) studies. Four observers at four different institutions independently evaluated aerosol-perfusion and gas-perfusion pairs, classifying the probability of PE as low, high, or indeterminate. The results suggest that radioaerosol inhalation studies, performed with improved nebulizers, are diagnostically equivalent to ventilation imaging as an adjunct to perfusion scintigraphy in evaluating patients with suspected PE.

• Research Organization: Columbia-Presbyterian Medical Center, New York, NY
• OSTI ID: 6349731
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 153:2; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AEROSOLS
AMINO ACIDS
ANIMAL TISSUES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
COLLOIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISPERSIONS
DRUGS
DTPA
ELECTRON CAPTURE RADIOISOTOPES
EMBOLI
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KRYPTON 81
KRYPTON ISOTOPES
LUNGS
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PERFUSED TISSUES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
RATS
RESPIRATORY SYSTEM
RODENTS
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
SOLS
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
VERTEBRATES
XENON 133
XENON ISOTOPES
YEARS LIVING RADIOISOTOPES