Pituitary and ovarian abnormalities demonstrated by CT and ultrasound in children with features of the McCune-Albright syndrome
In a random series of 97 children referred to the National Institutes of Health with a presumptive diagnosis of precocious puberty, eight girls were found to have features of the McCune-Albright syndrome, including fibrous dysplasia of bone and/or skin lesions resembling cafe au lait spots. Radiographic evaluation of these patients included computed tomography of the head and pelvic ultrasound. The pituitary glands were suspicious for abnormality in five of the eight girls. Seven girls underwent pelvic ultrasound, and in all of them the ovaries were considered to be abnormal for their chronological age; in addition, two had functional ovarian cysts. The role of diagnostic radiological studies in the diagnosis of this syndrome is discussed.
- Research Organization:
- National Institutes of Health, Bethesda, MD
- OSTI ID:
- 6349093
- Journal Information:
- Radiology; (United States), Journal Name: Radiology; (United States) Vol. 153:2; ISSN RADLA
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
BODY
BODY AREAS
CHILDREN
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
ENDOCRINE GLANDS
FEMALE GENITALS
GLANDS
GONADS
HEAD
ORGANS
OVARIES
PELVIS
PITUITARY GLAND
REPRODUCTIVE DISORDERS
TOMOGRAPHY
ULTRASONOGRAPHY