Relation between radiation resistance and salt sensitivity of spores of five strains of Clostridium botulinum types A, B, and E
The NaCl tolerance of different strains of Clostridium botulinum varies over a wide range, and the patterns of NaCl inhibition differ distinctly and characteristically from strain to strain. The more radiation-resistant strains, such as 33A, 62A, and 7272A, are more resistant to NaCl, whereas the more radiation-sensitive strains, such as 51B and 1304E, are more sensitive to NaCl. This rule appears to hold irrespective of whether the spores were unirradiated controls or whether they were radiation damaged prior to exposure to NaCl in the recovery media. The data seem to indicate that radiation doses in the shoulder portion of the radiation survival curves did not noticeably sensitize the spores to NaCl, whereas radiation doses in the exponential-decline portion of the survival curve invariably produced a distinct sensitization. Thus, strains 33A and 62A were not sensitized to NaCl by 0.3 to 0.4 Mrad, i.e., in the shoulder portion of the survival curve. Radiation-sensitive strain 51B, which shows no distinct shoulder in its survival curve, was sensitized to NaCl by 0.1 Mrad, the lowest radiation dose employed in this study. These observations seem to suggest a possible relationship between deoxyribonucleic acid repair capacity and salt tolerance.
- Research Organization:
- Meat Research Inst., Bristol, Eng.
- OSTI ID:
- 6339697
- Journal Information:
- Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 35:3; ISSN AEMID
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL COMPOUNDS
BACTERIA
BACTERIAL SPORES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL VARIABILITY
CHLORIDES
CHLORINE COMPOUNDS
CLOSTRIDIUM
CLOSTRIDIUM BOTULINUM
DOSE-RESPONSE RELATIONSHIPS
HALIDES
HALOGEN COMPOUNDS
MICROORGANISMS
RADIATION EFFECTS
RADIOSENSITIVITY
SENSITIVITY
SODIUM CHLORIDES
SODIUM COMPOUNDS
SPORES