Identification of the ftsA gene product. [uv radiation, Escherichia coli]
Journal Article
·
· J. Bacteriol.; (United States)
OSTI ID:6333167
A nonsense mutation was identified in the essential cell division gene ftsA of Escherichia coli. A lambda-transducing phage was isolated which complemented this mutation. This phage programmed the synthesis of four bacterial proteins in uv-irradiated cells. By substituting the nonsense mutation for the ftsA/sup +/ allele in this transducing phage and comparing the proteins programmed by it in uv-treated Su/sup +/ and Su/sup -/ cells, the product of the ftsA gene was identified as a protein with a molecular weight of 50,000.
- Research Organization:
- Univ. of Edinburgh, Scotland
- OSTI ID:
- 6333167
- Journal Information:
- J. Bacteriol.; (United States), Journal Name: J. Bacteriol.; (United States) Vol. 137:3; ISSN JOBAA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
BACTERIOPHAGES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOSYNTHESIS
DATA
DATA FORMS
ELECTROMAGNETIC RADIATION
ESCHERICHIA COLI
EXPERIMENTAL DATA
GENES
INFORMATION
ISOLATED VALUES
MICROORGANISMS
MUTATIONS
NUMERICAL DATA
ORGANIC COMPOUNDS
PARASITES
PROTEINS
RADIATION EFFECTS
RADIATIONS
SYNTHESIS
ULTRAVIOLET RADIATION
VIRUSES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
BACTERIOPHAGES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOSYNTHESIS
DATA
DATA FORMS
ELECTROMAGNETIC RADIATION
ESCHERICHIA COLI
EXPERIMENTAL DATA
GENES
INFORMATION
ISOLATED VALUES
MICROORGANISMS
MUTATIONS
NUMERICAL DATA
ORGANIC COMPOUNDS
PARASITES
PROTEINS
RADIATION EFFECTS
RADIATIONS
SYNTHESIS
ULTRAVIOLET RADIATION
VIRUSES