Intestinal absorption and biomagnification of organochlorines

Journal Article · Mon Mar 01 04:00:00 EST 1993 · Environmental Toxicology and Chemistry; (United States)

DOI:https://doi.org/10.1002/etc.5620120316· OSTI ID:6332158

Gobas, F A.P.C. ^[1]; McCorquodale, J R; Haffner, G D ^[2]

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1. Simon Fraser Univ., Burnaby, British Columbia (Canada)
2. Univ. of Windsor, Ontario (Canada)

Dietary uptake rates of several organochlorines from diets with different lipid contents were measured in goldfish (Carassius auratus) to investigate the mechanism of intestinal absorption and biomagnification of organic chemical. The results suggest that intestinal absorption is predominantly controlled by chemical diffusion rather than lipid cotransport. Data for chemical uptake in human infants are presented to illustrate that biomagnification is caused by the digestion of food in the gastrointestinal tract. The findings are discussed in the context of two conflicting theories for the mechanism of biomagnification, and a mechanistic model is presented for the dietary uptake and biomagnification of organic chemicals in fish and mammals.

• OSTI ID: 6332158
• Journal Information: Environmental Toxicology and Chemistry; (United States), Journal Name: Environmental Toxicology and Chemistry; (United States) Vol. 12:3; ISSN ETOCDK; ISSN 0730-7268
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
AQUATIC ORGANISMS
AROMATICS
BIOLOGICAL ACCUMULATION
CHLORINATED AROMATIC HYDROCARBONS
CONTAMINATION
FISHES
FOOD CHAINS
HALOGENATED AROMATIC HYDROCARBONS
INTESTINAL ABSORPTION
MATHEMATICAL MODELS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
SENSITIVITY
SORPTION
UPTAKE
VERTEBRATES
WATER POLLUTION