Evaluation of the clinical validity of the ''integral spleen'' method of renography analysis from parameter changes induced by pharmacological and surgical intervention

Journal Article · Thu Dec 31 23:00:00 EST 1987 · Am. J. Physiol. Imag.; (United States)

OSTI ID:6325108

Pilloy, W; Dormehl, I; Bosman, H; Maree, M; Hordijk, C; Hugo, N

A set of controlled experimental animal procedures involving pharmacological and surgical interventions was carried out to assess the clinical validity of the parameters calculated by the integral spleen method of renography analysis. There appeared to be a good correlation between the observed changes of these parameters and current pathophysiological information. In particular, the described method includes an original calculation of the filtration fraction without blood and urine sampling or a second tracer injection. This calculation was experimentally validated here.

• Research Organization: Medical Univ. of South Africa, Medunsa
• OSTI ID: 6325108
• Journal Information: Am. J. Physiol. Imag.; (United States), Journal Name: Am. J. Physiol. Imag.; (United States) Vol. 3:4; ISSN AJPIE
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BIOLOGICAL MODELS
BIOMEDICAL RADIOGRAPHY
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DTPA
ISOTOPES
KIDNEYS
MEDICINE
NUCLEAR MEDICINE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
RADIOLOGY
RADIOPROTECTIVE SUBSTANCES
SPLEEN
SURGERY
TECHNETIUM ISOTOPES
TESTING
UROGENITAL SYSTEM DISEASES
VALIDATION
VASOCONSTRICTION