Direct liquid sample introduction for flow injection analysis and liquid chromatography with inductively coupled argon plasma spectrometric detection

Journal Article · Tue Jan 31 23:00:00 EST 1984 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00266a038· OSTI ID:6322181

Lawrence, K E; Rice, G W; Fassel, V A

The coupling of flow injection analysis (FIA) or high-performance liquid chromatography (HPLC) techniques to inductively coupled plasma atomic emission spectrometry (ICP-AES) offers new and attractive approaches for the determination of elemental concentrations in a wide variety of sample matrices. One of the most attractive features that FIA offers is a rapid and precise means of automating sample introduction into an ICP for simultaneous, multielement analysis at the trace, minor, and major constituent level with minimal sample consumption. The utilization of the ICP as a detector for HPLC retains most of the advantages of FIA-ICP, while providing the analyst with a powerful and versatile means of compound separation. This added dimension becomes particularly important when metal speciation is of primary interest, rather than total metal content. To date, the coupling of FIA and HPLC to the ICP has only been accomplished using conventional cross-flow, concentric, or Babington-type pneumatic nebulizers. Limits of detection under these conditions have generally been observed to be poorer when compared to conventional continuous sample flow conditions. These limitations have been attributed to the large dead-volume and the sample losses associated with conventional nebulizers and band broadening of eluents from FIA transfer tubing or HPLC columns prior to entering the nebulizer unit. In an effort to resolve these difficulties, a microconcentric nebulizer has been developed which is inserted directly into the tip of a conventional sample introduction tube of an ICP torch. Preliminary data on the potential utility of direct liquid sample introduction into the ICP are presented. 12 references, 6 figures, 1 table.

• Research Organization: Ames Laboratory, IA
• DOE Contract Number: W-7405-ENG-82
• OSTI ID: 6322181
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 56:2; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
400104 -- Spectral Procedures-- (-1987)
ALKALINE EARTH METALS
ARSENIC
BARIUM
CADMIUM
CHEMICAL ANALYSIS
CHROMATOGRAPHY
CHROMIUM
COBALT
DATA
ELEMENTS
EMISSION SPECTROSCOPY
EXPERIMENTAL DATA
FLUID INJECTION
INFORMATION
LEAD
LIQUID COLUMN CHROMATOGRAPHY
MAGNESIUM
MANGANESE
MERCURY
METALS
NUMERICAL DATA
QUANTITATIVE CHEMICAL ANALYSIS
SELENIUM
SEMIMETALS
SEPARATION PROCESSES
SPECTROSCOPY
STRONTIUM
TRANSITION ELEMENTS